Depression

St. John's Wort (Western Capsule) is contraindicated for concomitant use because it induces CYP450 enzymes, which can lower blood SSRI levels or cause serotonin syndrome. However, this ingredient applies to Western herbal products and is not included in herbal medicines prescribed by domestic Korean medicine clinics. While herbal prescriptions—such as those that nourish both the mind and stomach, or those that relieve stuffiness by improving Qi circulation—rarely directly conflict with SSRIs, it is standard practice to verify the list of medications currently being taken before prescribing. At Dongjedang Korean Medicine Clinic, we always verify the type and dosage of antidepressants currently being taken during the initial consultation. We formulate a safe prescription by excluding ingredients with potential interactions. Bringing your prescription or providing the names of the medications will allow for a more accurate verification.